HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(bromomethyl)benzoate → 3-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
| Reactant | 2',4'-Dihydroxy-3'-propylacetophenone | HCID 2775198 | — |
| Product | 3-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]benzoic acid methyl ester | HCID 13912817 | — |
Reaction Steps
1-(2,4-dihydroxy-3-propylphenyl)ethanone was allowed to react with methyl 3-bromomethylbenzoate according to the procedure of Example 69 and the product was purified by recrystallization from methylene chloride-ether to give 3-[(4-acetyl-3-hydroxy-2-propylphenoxy)methyl]benzoic acid methyl ester, the title compound, mp 141°-143°, in 89% yield. Analysis Calculated for C20H22O5 : C, 70.16; H, 6.48. Found: C, 69.99; H, 6.41.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672066 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-41aeead6226943b69dd06cd25a26ec2f |
| Source note | uspto-grants-1987_06 |