Sodium Hydroxide → HCID 13912819, compound

HRID 652520Notes

Reaction equation

HRID 652520 reaction equation
C[O:2][C:3](=[O:25])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18](=[O:20])[CH3:19])=[C:14]([OH:21])[C:13]=1[CH2:22][CH2:23][CH3:24].[OH-].[Na+]>>[C:18]([C:15]1[CH:16]=[CH:17][C:12]([O:11][CH2:10][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([OH:25])=[O:2])=[C:13]([CH2:22][CH2:23][CH3:24])[C:14]=1[OH:21])(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 13912818HCID 13912818, compound

Product 1

HCID 13912819HCID 13912819, compound

Procedure

2-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]benzoic acid methyl ester was allowed to react with 1.0N sodium hydroxide according to the procedure of Example 70 and the product was purified by recrystallization from methanol to give 2-[(4-acetyl-3-hydroxy-2-propylphenoxy)methyl]benzoic acid, the title compound, m.p. 216°-219°, in 85% yield. Analysis Calculated for C19H20O5 : C, 69.50; H, 6.14. Found: C, 69.39; H, 6.19.

Workup

  1. customthe product was purified by recrystallization from methanol

Sources & evidence

ORD record
ord-fabbdcfbc0bb43d9b5a776a37c10e9be
Source dataset
uspto-grants-1987_06
Patent number
US04672066

Reaction notes

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