Sodium Hydroxide → HCID 13912821, compound

HRID 652522Notes

Reaction equation

HRID 652522 reaction equation
C([O:3][C:4](=[O:29])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][O:12][C:13]2[CH:18]=[CH:17][C:16]([C:19](=[O:21])[CH3:20])=[C:15]([OH:22])[C:14]=2[CH2:23][CH2:24][CH3:25])[C:6]=1[O:26][CH2:27][CH3:28])C.[OH-].[Na+]>>[C:19]([C:16]1[CH:17]=[CH:18][C:13]([O:12][CH2:11][C:7]2[C:6]([O:26][CH2:27][CH3:28])=[C:5]([CH:10]=[CH:9][CH:8]=2)[C:4]([OH:29])=[O:3])=[C:14]([CH2:23][CH2:24][CH3:25])[C:15]=1[OH:22])(=[O:21])[CH3:20]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 13912820HCID 13912820, compound

Product 1

HCID 13912821HCID 13912821, compound

Procedure

3[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]-2-ethoxybenzoic acid ethyl ester was allowed to react with 1.0N sodium hydroxide according to the procedure of Example 70 and the product was purified by recrystallization from methanol to give 3-[(4-acetyl-3-hydroxy-2-propylphenoxy)methyl]-2- ethoxybenzoic acid, the title compound, m.p. 154°-156° in 85% yield.

Workup

  1. customthe product was purified by recrystallization from methanol

Sources & evidence

ORD record
ord-a756ef714af443c88d973fc5e3f0cde8
Source dataset
uspto-grants-1987_06
Patent number
US04672066

Reaction notes

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