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HRID65253

反应详情

EQUATION

反应方程式

HRID 65253 的结构方程式

REACTANTS

反应物

2
结构：Cn1ccnc1
HCID1390

1-Methylimidazole

C4H6N2

结构：CS(=O)(=O)Nc1ccc(C(=O)CCl)cc1
HCID116629

Methanesulfonamide, N-[4-(chloroacetyl)phenyl]-

C9H10ClNO3S

PRODUCTS

生成物

1
结构：CN1C=C[NH+](CC(=O)c2ccc(NS(C)(=O)=O)cc2)C1.[Cl-]
HCID86741031

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Heat a mixture of 160 g (0.646 mole) of N-[4-(2- chloro-1-oxoethyl)phenyl]methanesulfonamide, 55.7 g (0.678 mole) of 1-methyl-1H-imidazole and 2.1 L of acetonitrile at reflux for about 16 hours. Cool the mixture to room temperature and collect the solid and wash with 2 L of acetonitrile. Drying provides the title compound, which may be recrystallized from aqueous ethanol.

WORKUP

后处理

  1. temperatureHeat
  2. temperatureat reflux for about 16 hours
  3. customcollect the solid
  4. washwash with 2 L of acetonitrile
  5. customDrying