HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(2-Bromoethyl)-4-(methoxymethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl benzenesulfonate | HCID 6630 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | [4-(2-Bromoethyl)phenyl]methanol | HCID 22337010 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(2-Bromoethyl)-4-(methoxymethyl)benzene | HCID 20197428 | — |
Reaction Steps
The 1-(2-bromoethyl)-4-hydroxymethylbenzene (0.5 g) is then added to a solution of 0.44 g methyl benzene-sulfonate and 0.32 g K2CO3 in 10 mL of methanol and allowed to react for 4 h. The solution is neutralized with methanolic HCl and extracted with ether. The ether extract is dried over Na2SO4, filtered, and the solvent removed under vacuum to yield 1-(methoxymethyl)-4-(2-bromoethyl)benzene (13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672071 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-f3d7f2735bef413f9bd37c0c5fba0c3a |
| Source note | uspto-grants-1987_06 |