Carbamic acid, ethyl ester → HCID 13765531, compound

Participants

Reaction Steps

35 g of methacrolein are added dropwise at 60°-65° C. to a mixture of 133.5 g of ethyl carbamate, 30 g of acid ion exchanger resin (Duolite C 265), 0.4 g of hydroquinone monomethyl ether and 400 ml of chloroform in the course of 40 minutes. The mixture is left at that temperature for 1 hour, the ion exchanger is filtered off, the chloroform is distilled off, and the residue is crystallized from ethyl acetate/petroleum ether. This gives 97 g of 2-methyl-1,1,3-tri(ethoxycarbonylamino)propane (60.8% yield, based on starting methacrolein) having a melting point of 138°-140° C.

Provenance & Evidence