HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13765533, compound → HCID 13765535, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13765533 | HCID 13765533 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13765535 | HCID 13765535 | 93.7% |
Reaction Steps
130 g of the 2-ethyl-1,1,3-tri(ethoxycarbonylamino)propane prepared in stage (a) are dissolved in 1300 ml of ethanol, 30 g of Raney nickel are added, and hydrogenation is carried out at 200 bar of hydrogen and 165° C. for 15 hours. Removal of the catalyst by filtration and of the solvent and ethyl carbamate by distillation leaves 90 g of 2-ethyl-1,3-di(ethoxycarbonylamino)propane having a purity of 94% (88% isolated yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04672137 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-76808bb4deb14ec28d537618c697e716 |
| Source note | uspto-grants-1987_06 |