HCID 13914720, compound → HCID 178491882, compound

HRID 652582Notes

Reaction equation

HRID 652582 reaction equation
NC1C2C(=CC=C3OC[O:12]C3=2)N=C([Cl:15])N=1.[NH2:16][C:17]1[C:26]2[C:21](=[C:22]([Cl:31])[CH:23]=[C:24]([O:29][CH3:30])[C:25]=2[O:27][CH3:28])[N:20]=[C:19](Cl)[N:18]=1.NC1C2C(=CC=C3OCOC3=2)N=C(O)N=1>>[ClH:15].[NH2:16][C:17]1[C:26]2[C:21](=[C:22]([Cl:31])[CH:23]=[C:24]([O:29][CH3:30])[C:25]=2[O:27][CH3:28])[N:20]=[C:19]([OH:12])[N:18]=1

Participants

4

Reactant 3

HCID 13914720HCID 13914720, compoundHCID 54084678HCID 54084678, compoundHCID 178508999HCID 178508999, compound

Product 1

HCID 178491882HCID 178491882, compound

Procedure

When in the above procedure 4-amino-2-chloro-5,6-methylenedioxyquinazoline is substituted for 4-amino-2,8-dichloro-5,6-dimethoxyquinazoline the corresponding 4-amino-5,6-methylenedioxy-2-hydroxyquinazoline is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-84ae65f5daaf42f1a17206b022c1a44c
Source dataset
uspto-grants-1987_06
Patent number
US04672116

Reaction notes

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