Sodium Methoxide → HCID 88661886, compound

HRID 652586Notes

Reaction equation

HRID 652586 reaction equation
[CH3:1][O-].[Na+].[Cl:4][C:5]1[N:14]=[C:13]([O:15][CH3:16])[C:12]2[C:7](=[C:8]([Cl:21])[CH:9]=[C:10]([O:19][CH3:20])[C:11]=2[O:17][CH3:18])[N:6]=1>>[OH2:15].[Cl:4][C:5]1[N:14]=[C:13]([O:15][CH2:16][CH3:1])[C:12]2[C:7](=[C:8]([Cl:21])[CH:9]=[C:10]([O:19][CH3:20])[C:11]=2[O:17][CH3:18])[N:6]=1.[Cl:4][C:5]1[N:14]=[C:13]([O:15][CH2:16][CH3:1])[C:12]2[C:7](=[C:8]([Cl:21])[CH:9]=[C:10]([O:19][CH3:20])[C:11]=2[O:17][CH3:18])[N:6]=1

Participants

3

Reactant 2

HCID 10942334Sodium MethoxideHCID 20197772HCID 20197772, compound

Product 1

HCID 88661886HCID 88661886, compound

Procedure

When, in the above procedure, sodium methoxide is employed in place of sodium ethoxide the corresponding 2,8-dichloro-4-methoxy-5,6-dimethoxyquinazoline is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-7825139b0cff45d98c33c06fc0f14238
Source dataset
uspto-grants-1987_06
Patent number
US04672116

Reaction notes

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