Hydrazine → HCID 13914727, compound

Participants

Reaction Steps

A mixture of 4-amino-2,8-dichloro-5,6-dimethoxyquinazoline (1.5 g, 0.0054 moles), anhydrous hydrazine (5 ml, 0.16 moles) and methanol (100 ml) was heated at reflux for 8 hours and stirred at room temperature for 16 hours. The mixture was cooled to 0° C. and the precipitate which formed was collected by filtration. Recrystallization of the solid from methanol followed by drying under vacuum at 55° C. afforded the product (1.12 g), mp 168°-169° C.

Provenance & Evidence