Anthranilic Acid → 2-Aminobenzoic acid--nickel (1/1)
Reaction equation
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[OH-].[Na+].[Ni:13](Cl)Cl>O>[Ni:13].[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 80 °C
Procedure
54.8 g (0.4 mol) of anthranilic acid was completely dissolved in a solution obtained by dissolving 16 g (0.4 mol) of caustic soda in 1 liter of water. The solution was heated to 80° C., and a solution of 25.9 g (0.2 mol) of nickel chloride in 150 ml of water was gradually added dropwise to the heated solution. After the addition, the mixture was stirred for 1 hour at 80° C. and then allowed to be cooled down to room temperature under stirring. After the cooling, the resultant precipitate was filtered out and washed with water until the filtrate water reached neutrality. After washing, the precipitate was dried at 90° C. to obtain about 65 g of pale blue powder.
Workup
- customobtained
- additionAfter the addition
- temperatureto be cooled down to room temperature
- stirringunder stirring
- filtrationAfter the cooling, the resultant precipitate was filtered out
- washwashed with water until the filtrate water reached neutrality
- washAfter washing
- customthe precipitate was dried at 90° C.
Sources & evidence
- ORD record
- ord-aaf85464986a4886ae2a3d1bfe94aeba
- Source dataset
- uspto-grants-1987_06
- Patent number
- US04673631
Reaction notes
Loading…