HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 20196858, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzoic acid, 3,5-dichloro-2-hydroxy-, methyl ester | HCID 82082 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 20196858 | HCID 20196858 | — |
Reaction Steps
A 5 liter flask fitted with a sealed agitator, a condenser and a thermometer is used. 320 g of methyl 3,5-dichlorosalicylate (1.45 mole), 1,280 ml of methyl-ethyl-ketone and 177 g of propargyl bromide (1.45 mole+3% excess) are placed in it, then 200 g of potassium carbonate (1.45 mole) and 21.5 g of sodium iodide (0.145 mole). A thick pulp is obtained, which becomes fluid when brought to reflux. The reflux is maintained for 8 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04673686 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-49a64461211c420aafd60bd0bd63b137 |
| Source note | uspto-grants-1987_06 |