HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Chloride → 2-Chloro-3-benzyloxy-4-methoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Chloroisovaniline | HCID 603956 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Chloro-3-benzyloxy-4-methoxybenzaldehyde | HCID 11747833 | — |
Reaction Steps
A mixture of 78 g of 2-chloro-3-hydroxy-4-methoxybenzaldehyde, 60.7 g of benzyl chloride, 3.9 g of sodium jodide, 74.6 g of potassium carbonate in 0.5 l of 95% ethanol was refluxed for 2 hours. After cooling the mixture was poured in water, the separated product was filtered and then recrystallized from absolute ethanol. 2-chloro-3-benzyloxy-4-methoxybenzaldehyde was obtained, m.p. 86°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04673671 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-ba149259e75c4324a9cf07c799f34f61 |
| Source note | uspto-grants-1987_06 |