HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 20196967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Amino-6-chlorobenzoic acid | HCID 75071 | — |
| Reactant | HCID 20196974 | HCID 20196974 | — |
| Catalyst | Benzyltrimethylammonium chloride | HCID 5963 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 20196967 | HCID 20196967 | 99% |
Reaction Steps
When 42.9 g of 6-chloroanthranilic acid, 58.4 g of 3-chlorodifluoromethoxybenzoyl fluoride, 20.8 g of 50% strength sodium hydroxide solution, 0.45 g of benzyltrimethylammonium chloride, 700 g of 1,2-dichloroethane and 32.7 g of thionyl chloride are used as starting materials and the procedure described in Example 1 is employed, 88.6 g (99%) of 5-chloro-2-(m-chlorodifluoromethoxyphenyl)-4H-3,1-benzoxazin-4-one of melting point 112°-114° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04673740 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-3d3e651214464be1b241ead80d19c2d5 |
| Source note | uspto-grants-1987_06 |