2,3-Dichloroanisole → HCID 14012560, compound

HRID 652864Notes

Reaction equation

HRID 652864 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[Al+3].[Cl-].[Cl-].[Cl-].[Cl:15][C:16]1[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:17]=1[O:23][CH3:24]>>[Cl:22][C:21]1[C:16]([Cl:15])=[C:17]([O:23][CH3:24])[CH:18]=[CH:19][C:20]=1[C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[Cl:1])=[O:5]

Participants

4

Reactant 3

HCID 161262,3-DichloroanisoleHCID 691102-Chlorobenzoyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 14012560HCID 14012560, compound

Procedure

The Friedel-Crafts procedure of Example 24a is repeated with 48.13 g of o-chlorobenzoyl chloride being combined with 36.7 g AlCl3 and 44.26 g of 2,3-dichloroanisole to yield a white crystalline product of 2,3-dichloro-4-methoxy-2'-chlorobenzophenone, mp 117°-120° C.

Sources & evidence

ORD record
ord-1155d886fdba4be396abdf380c9df8b5
Source dataset
uspto-grants-1987_06
Patent number
US04673746

Reaction notes

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