Acetic Acid → HCID 54235086, compound

Participants

Reaction Steps

To a solution of 56 mg (0.12 mmol) of the amide compound prepared above in 1 ml of dioxane was added 4 ml of 80% acetic acid. The mixture was heated under reflux for 2 hours. Water was added to the reaction solution, and crystals then formed were isolated by filtration and recrystallized from methanol. There was obtained 24 mg (0.65 mmol) of N-{5-(3,5-dimethoxy-4-hydroxyphenyl)-2,4-pentadienoyl}anthranilic acid. Spectrophotometric data of the product support the structure shown below. ##STR69##

Provenance & Evidence