N,N-Diethyl-1,3-propanediamine → HCID 13531622, compound

HRID 653094Notes

Reaction equation

HRID 653094 reaction equation
Br[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([N+:11]([O-:13])=[O:12])=[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[CH:20]=1.[CH2:21]([N:23]([CH2:26][CH2:27][CH2:28][NH2:29])[CH2:24][CH3:25])[CH3:22]>C(O)C>[CH2:21]([N:23]([CH2:26][CH2:27][CH2:28][NH:29][CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([N+:11]([O-:13])=[O:12])=[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[CH:20]=1)[CH2:24][CH3:25])[CH3:22]

Participants

4

Reactant 2

HCID 61011N,N-Diethyl-1,3-propanediamineHCID 13531604HCID 13531604, compound

Product 1

HCID 13531622HCID 13531622, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using the method of Example 1, 5-bromomethyl-2-nitro-3-phenylbenzofuran is reacted with 3-(N,N-diethylamino)propylamine in ethanol to provide light tan crystals of 5-[3-(N,N-diethylamino)propylaminomethyl]-2-nitro-3-phenylbenzofuran dihydrochloridemonohydrate, m.p. 143°-150° C., having the structure

Sources & evidence

ORD record
ord-fef420c66c204a47a5dcfc98cdb8e468
Source dataset
uspto-grants-1987_06
Patent number
US04675320

Reaction notes

Loading…