Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 178420131 | HCID 178420131 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178419493 | HCID 178419493 | — |
Reaction Steps
To a stirred solution of 2.8 g. (0.01 mole) of 5-tetrazolylmethyl-3-phenylbenzofuran in 100 ml. of chloroform and 20 ml. of dioxane is added dropwise 1.6 g. (0.01 mole) of bromine. After 45 minutes the mixture is cooled to 0° C., then the product is separated by filtration and washed with chloroform. Recrystallization from aqueous ethanol provides 2-bromo-3-phenyl-5-(1H-tetrazol-5yl)methylbenzofuran m.p. 215°-217° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04675320 |
|---|
| Source dataset | uspto-grants-1987_06 |
|---|
| ORD ID | ord-b91444db6ad744ef89ac85a1521fee57 |
|---|
| Source note | uspto-grants-1987_06 |
|---|
