HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epichlorohydrin → 4-Chloro-4'-[(2,3-epoxypropyl)amino]benzophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Amino-4'-chlorobenzophenone | HCID 3528706 | — |
| Product | 4-Chloro-4'-[(2,3-epoxypropyl)amino]benzophenone | HCID 20186592 | — |
Reaction Steps
23.2 g of 4-chloro-4'-aminobenzophenone, 92 g of epichlorohydrin and 7 g of potassium carbonate were heated at reflux for 15 hours. The excess epichlorohydrin was evaporated in vacuo and the solid residue was partitioned between water and chloroform. From the organic phase there was obtained 4-chloro-4'-[(2,3-epoxypropyl)amino]benzophenone which was recrystallized twice from methanol, m.p. 128°-129° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04675328 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-bb31ad61fbdb454f81bfb79e92d6882c |
| Source note | uspto-grants-1987_06 |