HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 5-Methoxy--methyl-3-(1-methylethoxy)-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 13885830 | HCID 13885830 | — |
| Product | 5-Methoxy--methyl-3-(1-methylethoxy)-1H-indole-2-carboxylic acid | HCID 13885799 | 47% |
Reaction Steps
Prepared by the saponification procedure described in Example 7 from 41.2 g (0.15 mole) of 5-methoxy-1-methyl-3-(1-methylethoxy)-1H-indole-2-carboxylic acid methyl ester and 16.7 g (0.30 mole) of potassium hydroxide. The crude acid product was 18.3 g (47% yield). A sample recrystallized from aqueous 2-methoxyethanol was analytically pure, mp 110°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04675332 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-a9e59446fd884dd38fb92e098817c8f9 |
| Source note | uspto-grants-1987_06 |