2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-methoxynaphthalen-2-yl)prop-2-enoic Acid

HRID 653214Notes

Reaction equation

HRID 653214 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([CH3:17])[C:14]([OH:16])=[O:15])[CH:7]=[CH:6]2.C[C@H](C(O)=O)C1C=CC2C=C(OC)C=CC=2C=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13](=[CH2:17])[C:14]([OH:16])=[O:15])[CH:7]=[CH:6]2

Participants

3

Reactant 2

HCID 13022-(6-Methoxy-2-naphthyl)propionic acidHCID 156391Naproxen

Product 1

HCID 37179052-(6-methoxynaphthalen-2-yl)prop-2-enoic Acid

Procedure

Using the method described in Example 1 b) 2-(6-methoxy-2-naphthyl)-propionic acid or naproxen in DL-form was obtained from 2-(6-methoxy-2-naphthyl)-propenoic acid.

Sources & evidence

ORD record
ord-f9853100bd0b477bbe051ee459deafd6
Source dataset
uspto-grants-1987_06
Patent number
US04675419

Reaction notes

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