Water → HCID 86741636, compound

HRID 653217Notes

Reaction equation

HRID 653217 reaction equation
[P:1]([O-:6])([O:4]C)[O:2]C.O.[CH2:8]([O:12][CH2:13][CH2:14][CH2:15][NH2:16])[CH2:9][CH2:10][CH3:11]>CO>[CH3:8][P:1](=[O:6])([O-:4])[O-:2].[CH2:8]([O:12][CH2:13][CH2:14][CH2:15][NH3+:16])[CH2:9][CH2:10][CH3:11].[CH2:8]([O:12][CH2:13][CH2:14][CH2:15][NH3+:16])[CH2:9][CH2:10][CH3:11]

Participants

5

Reactant 3

HCID 962WaterHCID 854611-Propanamine, 3-butoxy-HCID 21884954Dimethylphosphite

Product 1

HCID 86741636HCID 86741636, compoundYield 89.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A mixture of 11 g. (0.1 moles) of dimethyl phosphite, 20 ml. of water and 20 ml. of methanol is reacted with a mixture of 13.12 g. (0.1 moles) of 3-butyloxypropyl amine and 30 ml. of methanol as described in Example 1. 22.6 g. of 3-butyloxypropyl-ammoniummethyl phosphonate are obtained. Yield: 89.4%. nD30 =1.4420

Workup

  1. additionA mixture of 11 g

Sources & evidence

ORD record
ord-0fdd54443390422a927ac9a67509f300
Source dataset
uspto-grants-1987_06
Patent number
US04675431

Reaction notes

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