Water → 1-Methyl-2-phenoxyethyl-ammoniumethyl phosphonate

HRID 653222Notes

Reaction equation

HRID 653222 reaction equation
[P:1]([O-:8])([O:5]CC)[O:2]CC.O.[CH3:10][CH:11]([NH2:20])[CH2:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[CH2:10]([P:1](=[O:2])([O-:5])[O-:8])[CH3:11].[CH3:10][CH:11]([NH3+:20])[CH2:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[CH3:10][CH:11]([NH3+:20])[CH2:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

5

Reactant 3

HCID 962WaterHCID 370871-Phenoxy-2-propanamineHCID 3780918Diethylphosphite

Product 1

HCID 867414541-Methyl-2-phenoxyethyl-ammoniumethyl phosphonateYield 81.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A mixture of 13.81 g. (0.1 moles) of diethyl phosphite, 20 ml. of water and 20 ml. of ethanol is reacted with a mixture of 15.12 g. (0.1 moles) of 1-methyl-2-phenoxyethyl amine and 30 ml. of ethanol as described in Example 1. 21.4 g. of 1-methyl-2-phenoxyethyl-ammoniumethyl phosphonate is obtained. Yield: 81.9%. Melting point: 95°-96° C.

Workup

  1. additionA mixture of 13.81 g

Sources & evidence

ORD record
ord-1a4c5bcc49e14a968e01597bd5e6c787
Source dataset
uspto-grants-1987_06
Patent number
US04675431

Reaction notes

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