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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 653433Generated: October 30, 2026

Benzyl Bromide → HCID 53799587, compound

https://huagongshe.com/reaction/653433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 13603775HCID 13603775—
CatalystTetrabutylammonium BromideHCID 74236—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
ProductHCID 53799587HCID 53799587—

Reaction Steps

A solution of 20.5 g of 2,3-dihydro-2-oxo-1H-indole-7-acetic acid (0.1 mole) and 4.0 g (0.1 mole) of sodium hydroxide in 200 ml of water is vigorously stirred together with a solution of 20.5 g (0.12 mole) of benzyl bromide and 3.4 g (0.1 mole) of tetrabutylammonium bromide in 300 ml of toluene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04677112
Source datasetuspto-grants-1987_06
ORD IDord-99ed21b8a9ef4c3987bcc7594c03c59c
Source noteuspto-grants-1987_06