HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-n-Decyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione → 1-(4-Amino-phenyl)-3-decyl-3-aza-bicyclo[3.1.1]heptane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-n-Decyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872616 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 2-Methoxyethanol | HCID 8019 | — |
| Product | 1-(4-Amino-phenyl)-3-decyl-3-aza-bicyclo[3.1.1]heptane-2,4-dione | HCID 14872623 | — |
Reaction Steps
In a manner analogous to that described in Example 1a, 6.0 g of 3-n-decyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]-heptane-2,4-dione are dissolved in 120 ml of 2-methoxyethanol, hydrogenated in the presence of 0.6 g of 5% palladium-on-carbon and worked up. Melting point 81.5°-82.5° (from ethyl acetate/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04677129 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-8fe025d6ae3a46338cbfde7744ed9f17 |
| Source note | uspto-grants-1987_06 |