HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 1-(4-Aminophenyl)-3-n-butyl-3-azabicyclo[3.1.1]heptane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 3-n-Butyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 20027825 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4-Aminophenyl)-3-n-butyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 20027835 | — |
Reaction Steps
In a manner analogous to that described in Example 1, 2.08 g of 3-n-butyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione in 60 ml of ethanol are hydrogenated in the presence of 0.15 g of palladium-on-carbon and worked up. Melting point 178°-179° (from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04677129 |
| Source dataset | uspto-grants-1987_06 |
| ORD ID | ord-f42a7228885d4602b39d28f643c4ef82 |
| Source note | uspto-grants-1987_06 |