Bromide ion → HCID 20195029, compound

Participants

Reaction Conditions

Reaction Steps

6.7 g of bromide are added dropwise to a mixture of 7.92 g of 3,4-dihydro-2,2-dioxo-3-methyl-1,2-benzoxathiine, 6.5 g of sodium acetate, 0.1 g of iodine and 60 ml of glacial acetic acid, which is then stirred for 24 hours at a temperature of 40° C. The mixture is concentrated and taken up with a mixture of water and ethyl acetate. The organic phase is separated, twice washed with an aqueous solution of sodium hydrogen-carbonate, dried and evaporated. The oily residue is introduced into the following reaction step without further purification operations.

Provenance & Evidence