4-Hydroxybenzoic Acid → HCID 54110816, compound

HRID 653588Notes

Reaction equation

HRID 653588 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[CH3:11][C@@H:12]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[C:13](Cl)=[O:14]>>[CH3:11][C@@H:12]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[C:13]([O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)=[O:14]

Participants

3

Reactant 2

HCID 1354-Hydroxybenzoic AcidHCID 54188531HCID 54188531, compound

Product 1

HCID 54110816HCID 54110816, compoundYield 32.6%

Procedure

Using p-hydroxybenzoic acid (3.25 g, 23.5 mmol) and (S)-2-methyldecanoylchloride (4.83 g, 23.6 mmol), the reaction was carried out in the same manner as described in Example 4, (1}, to give 2.35 g of the title compound as white crystals; mp. 92.5°-96.5° C.

Sources & evidence

ORD record
ord-126b150e7e8e498e91f8fa27f92e85bb
Source dataset
uspto-grants-1992_07
Patent number
US05128062

Reaction notes

Loading…