(R)-2-n-hexyloxypropanoyl chloride → HCID 178445064, compound

HRID 653591Notes

Reaction equation

HRID 653591 reaction equation
[OH:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1.[CH2:11]([O:17][C@H:18]([CH3:22])[C:19](Cl)=[O:20])[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]>>[CH2:11]([O:17][C@H:18]([CH3:22])[C:19]([O:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([C:8]([OH:10])=[O:9])[CH2:4][CH2:3]1)=[O:20])[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 22844813(R)-2-n-hexyloxypropanoyl chlorideHCID 178525780HCID 178525780, compound

Product 1

HCID 178445064HCID 178445064, compound

Procedure

Using trans-4-hydroxycyclohexane carboxylic acid (1.01 g, 7 mmol) and (R)-2-n-hexyloxypropanoyl chloride (1.35 g, 7 mmol), the reaction was carried out in the same manner as described in Example 4, (1), to give the title compound as a pale yellow oil; yield: 750 mg.

Sources & evidence

ORD record
ord-d3403ec324124f6ebcef953fdb93a990
Source dataset
uspto-grants-1992_07
Patent number
US05128062

Reaction notes

Loading…