HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methyl-3-nitropyridine → 4-Methylpyridine-2,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methyl-3-nitropyridine | HCID 243166 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Methylpyridine-2,3-diamine | HCID 317495 | — |
Reaction Steps
To a slurry of 2-amino-4-methyl-3-nitropyridine (10.0 g, 65.3 mmol) in 350 ml of 95% EtOH was added 500 mg of a 10% Pd/C catalyst. The mixture was stirred under a H2 atmosphere (1 atm) for 36 hours. Filtration and evaporation gave a black solid which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05128327 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-4b4f4de9226447649dc403190dcf77f6 |
| Source note | uspto-grants-1992_07 |