Ammonium Chloride → HCID 178468762, compound

Participants

Reaction Steps

A mixture of ethyl 1-[(2'-cyanobiphenyl-4yl)methyl]-2-ethylbenzimidazole-7-carboxylate (1.55 g), sodium azide (2.6 g) and ammonium chloride (2.14 g) in DMF (15 ml) was stirred for 5 days at 110°-120 C. The reaction mixture was worked up according to the procedure described in Working Example 23 to give crystals. Recrystallization from ethanol afforded colorless prisms (0.68 g, 40%), m.p. 188°-189° C.

Provenance & Evidence