N-Iodosuccinimide → HCID 15029852, compound

HRID 653747Notes

Reaction equation

HRID 653747 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.[I:12]N1C(=O)CCC1=O>CC#N>[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[I:12])[C:7](=[O:11])[CH2:6][CH2:5]2

Participants

4

Reactant 2

HCID 120273N-IodosuccinimideHCID 2331475-Hydroxy-1-indanone

Product 1

HCID 15029852HCID 15029852, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

5-Hydroxy-1 indanone (1.48 g),-N-iodosuccinimide (2.25 g) and CH3CN (20 ml) were stirred at room temperature overnight. The solution was evaporated to dryness, slurried with EtOAc, then filtered. The filtrate was evaporated to dryness and the solid recrystallized from CH3CN affording the desired compound (0.92 g), m.p. 114°-15° C.

Workup

  1. customThe solution was evaporated to dryness
  2. filtrationfiltered
  3. customThe filtrate was evaporated to dryness
  4. customthe solid recrystallized from CH3CN affording the desired compound (0.92 g), m.p. 114°-15° C.

Sources & evidence

ORD record
ord-00e0880a6da042dc97cc65b77d8c0fa7
Source dataset
uspto-grants-1992_07
Patent number
US05128362

Reaction notes

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