HCID 13340044, compound → HCID 19882627, compound

HRID 653749Notes

Reaction equation

HRID 653749 reaction equation
[ClH:1].[F:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[C:9]([CH2:13][NH2:14])=[CH:8][CH2:7][CH2:6]2>C(O)(=O)C>[ClH:1].[F:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]([CH2:13][NH2:14])[CH2:8][CH2:7][CH2:6]2

Participants

3

Reactant 1

HCID 13340044HCID 13340044, compound

Product 1

HCID 19882627HCID 19882627, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The product from Example 74 was reduced as in Example 2 but replacing the NH3 with acetic acid and afforded the desired compound, m.p. 236°-38° C.

Sources & evidence

ORD record
ord-5fba863a83894c4099733f1042cdce78
Source dataset
uspto-grants-1992_07
Patent number
US05128362

Reaction notes

Loading…