HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → 4-Hexadecyloxyphenoxyacetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | 4-(Hexadecyloxy)phenol | HCID 4377937 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-Hexadecyloxyphenoxyacetic acid methyl ester | HCID 10250794 | 89.4% |
Reaction Steps
A mixture of 23 g of p-(hexadecyloxy)phenol, 13.35 g of methyl bromoacetate, 10.45 g of potassium carbonate in 200 ml of acetone is refluxed for 24 hours. The mixture is cooled, chloroform added and filtered. The filtrate is evaporated and the residue crystallized from hexane to give 25 g of the desired compound as a gray white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05128351 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-b490d00acbfd48f4bcbc57a2918fc30f |
| Source note | uspto-grants-1992_07 |