Hydrochloride methanol → HCID 88147002, compound

HRID 653862Notes

Reaction equation

FC(F)(F)C([O-])=O.C([NH:10][C@@H:11]1[C:33](=[O:34])[N:13]2[C:14]([C:30]([OH:32])=[O:31])=[C:15](/[CH:18]=[CH:19]/[CH2:20][N+:21]([C@@H:24]([C:27](=[O:29])[NH2:28])[CH2:25][OH:26])([CH3:23])[CH3:22])[CH2:16][S:17][C@H:12]12)=O.[ClH:35].CO>>[ClH:35].[NH2:10][C@@H:11]1[C:33](=[O:34])[N:13]2[C:14]([C:30]([O-:32])=[O:31])=[C:15](/[CH:18]=[CH:19]/[CH2:20][N+:21]([C@@H:24]([C:27](=[O:29])[NH2:28])[CH2:25][OH:26])([CH3:23])[CH3:22])[CH2:16][S:17][C@H:12]12

Participants

Reactant 2

HCID 21893726Hydrochloride methanol

HCID 131717454HCID 131717454, compound

Product 1

HCID 88147002HCID 88147002, compound

Procedure

In a similar manner as in Example 24, the compound (4 g) of Example 29 was stirred in a 4% (w/w) hydrochloric acid-methanol solution (40 ml) to obtain the target product (2.57 g).

Sources & evidence

ORD record: ord-7d474cee459e498e8e5f11eb4895ae8f
Source dataset: uspto-grants-1992_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05128465

Reaction notes

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