Diethyl Ether → HCID 14621660, compound

Participants

Reaction Steps

The compound (500 mg) of Example 38 was suspended in anisole (3 ml), followed by an addition of trifluoroacetic acid (3.5 ml) under ice cooling. The resulting mixture was stirred for 1 hour at the same temperature, followed by a further addition of trifluoroacetic acid (1.5 ml). The resulting mixture was stirred for 1 hour. Ethyl ether was added, and a precipitate thus formed was collected by filtration to obtain the target product (350 mg). Its infrared spectrum and NMR spectrum were consistent with those of Example 10.

Provenance & Evidence