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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 653967Generated: October 30, 2026

3-Cyclopentylpropionyl chloride → (4S)-benzyl-3-(3-cyclopentylpropanoyl)oxazolidin-2-one

https://huagongshe.com/reaction/653967

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyclopentylpropionyl chlorideHCID 66039—
Reactant(S)-4-Benzyl-2-oxazolidinoneHCID 736225—
Product(4S)-benzyl-3-(3-cyclopentylpropanoyl)oxazolidin-2-oneHCID 1107747996.6%

Reaction Steps

Following the procedure described in Example 45, 6.4 g of cyclopentane propionyl chloride and 7.1 g of (S)-4-phenylmethyl-2-oxazolidinone yielded 11.6 g of (S)-3-[3-cyclopentyl-1-oxopropyl]-4-(phenylmethyl)-2-oxazolidinone. [α]D25 =+99.61°

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05128448
Source datasetuspto-grants-1992_07
ORD IDord-67b6e06b86c344518f83cfcb83a74774
Source noteuspto-grants-1992_07