HRID65400

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID612

Lactic acid

C3H6O3

HCID702

Ethanol

C2H6O

结构：CC(O)CNCCNc1ccc(NCCNCC(C)O)c2c1C(=O)c1c(O)ccc(O)c1C2=O

HCID433060

1,4-dihydroxy-5,8-bis[2-(2-hydroxypropylamino)ethylamino]anthracene-9,10-dione

C24H32N4O6

PRODUCTS

生成物

结构：CC(O)C(=O)O.CC(O)C(=O)O.CC(O)CNCCNc1ccc(NCCNCC(C)O)c2c1C(=O)c1c(O)ccc(O)c1C2=O

HCID131711738

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A mixture of 228 mg. of 1,4-bis[2-(2- hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone, 120 mg. of 80% DL-lactic acid, and 10 ml. of ethanol is heated on a steam bath for 10 minutes, cooled, treated with 50 ml. of acetone and cooled to obtain the title compound.

WORKUP

后处理

additionA mixture of 228 mg
temperaturecooled
additiontreated with 50 ml

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9c4bb4e21d134267b17ad23616663b7f
来源数据集: uspto-grants-1986_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04614618
来源说明: uspto-grants-1986_09

反应 SMILES

[OH:1][CH:2]([CH3:34])[CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH:31]([OH:33])[CH3:32])=[CH:10][CH:9]=1.[C:35]([OH:40])(=[O:39])[CH:36]([CH3:38])[OH:37].C(O)C>CC(C)=O>[C:35]([OH:40])(=[O:39])[CH:36]([CH3:38])[OH:37].[C:35]([OH:40])(=[O:39])[CH:36]([CH3:38])[OH:37].[OH:1][CH:2]([CH3:34])[CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH:31]([OH:33])[CH3:32])=[CH:10][CH:9]=1