Formic Acid → HCID 15056490, compound

HRID 654151Notes

Reaction equation

HRID 654151 reaction equation
[CH3:1][O:2][CH2:3][C:4]1([CH3:23])[CH:13]([OH:14])[CH:12]([N:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]2=[O:21])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:22])[CH:10]=2)[O:5]1.[CH:24](O)=[O:25]>N1C=CC=CC=1>[CH3:1][O:2][CH2:3][C:4]1([CH3:23])[CH:13]([OH:14])[CH:12]([N:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]2=[O:21])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH:22][CH:24]=[O:25])[CH:10]=2)[O:5]1

Participants

4

Reactant 2

HCID 284Formic AcidHCID 15056488HCID 15056488, compound

Product 1

HCID 15056490HCID 15056490, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A solution of 1 g of 2-methoxymethyl-2-methyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-amino-3-chromanol in 15 ml of formic acid and 1 ml of pyridine is boiled for 24 hours and evaporated. Customary working up gives 2-methoxymethyl-2-methyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-formamido-3-chromanol.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-55d0b1e980224972a05bab0ecf95cb78
Source dataset
uspto-grants-1992_07
Patent number
US05130322

Reaction notes

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