Acetic Anhydride → HCID 15056491, compound

HRID 654152Notes

Reaction equation

HRID 654152 reaction equation
[CH3:1][O:2][CH2:3][C:4]1([CH3:23])[CH:13]([OH:14])[CH:12]([N:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]2=[O:21])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:22])[CH:10]=2)[O:5]1.[C:24](OC(=O)C)(=[O:26])[CH3:25]>N1C=CC=CC=1>[CH3:1][O:2][CH2:3][C:4]1([CH3:23])[CH:13]([OH:14])[CH:12]([N:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]2=[O:21])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH:22][C:24](=[O:26])[CH3:25])[CH:10]=2)[O:5]1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 15056488HCID 15056488, compound

Product 1

HCID 15056491HCID 15056491, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A mixture of 1 g of 2-methoxymethyl-2-methyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-amino-3-chromanol, 10 ml of acetic anhydride and 10 ml of pyridine is allowed to stand at 20° C. for 24 hours. The mixture is evaporated, worked up in the customary manner and 2-methoxymethyl-2-methyl-4-(1,2-dihydro-2-oxo-1-pyridyl)-6-acetamido-3-chromanol is obtained.

Workup

  1. customThe mixture is evaporated

Sources & evidence

ORD record
ord-135751228c4b40b8bd8becd71f6b1c63
Source dataset
uspto-grants-1992_07
Patent number
US05130322

Reaction notes

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