反应详情

Each 10 ml of the above suspensions of the treated microbial cells and 10 ml of a suspension of untreated microbial cells obtained similarly as in Example 1 was admixed with each 10 ml of a reaction substrate solution (pH 7.0) containing 20 mM 1,2,4-triazole-3-carboxamide, 20 mM inosine and 25 mM monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 24 hours. Analysis of ribavirin yields gave the results as shown in Table 4.