HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monobasic potassium phosphate → Ribavirin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monobasic potassium phosphate | HCID 516951 | — |
| Reactant | HCID 178513825 | HCID 178513825 | — |
| Reactant | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol | HCID 178521066 | — |
| Product | Ribavirin | HCID 37542 | 72.55% |
Reaction Steps
The above cell suspension was added to 800 ml of an aqueous solution containing 50 mM 1,2,4-triazole-3-carboxamide, 75 mM inosine and 50 mM monopotassium dihydrogen phosphate, and the reaction was carried out at 60° C. for 24 hours to give a ribavirin yield of 72.55%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04614719 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-54f80f80ac274c9a93447d460ff98ed6 |
| Source note | uspto-grants-1986_09 |