Water → HCID 54003692, compound

Participants

Reaction Steps

To a slurry of LiAlH4 (6.5 g; 0.17 mmol) in 250 ml of tetrahydrofuran (THF) at 0° C. was added 2-(2-propynylthio)benzoic acid (28.8 g; 0.15 mmol). The reaction mixture was allowed to warm to room temperature. To the reaction mixture was added 6.5 ml of water, then 6.5 ml of 15% NaOH and 13.0 ml of water. The mixture was filtered through diatomaceous earth (Celite,) and concentrated to afford 22 g of the subtitle compound.

Provenance & Evidence