Hydrochloric Acid → HCID 54364024, compound

Participants

Reaction Steps

To a solution of 0.38 g of farnesyl 5-(4-ethoxycarbonyloxy-3-methoxyphenyl)-2,4-pentadienoate in 10 ml of methanol are added 2 ml of water and 0.08 g of sodium carbonate followed by stirring for 3 hours. To the reaction mixture is added 10 ml of water. The mixture is acidified with 1N hydrochloric acid and then extracted with chloroform. The organic layer is washed with saturated aqueous sodium chloride and dried over anhydrous sodium sulfate. The solvent is then distilled off under reduced pressure, and the residue is subjected to column chromatography on silica gel. From the fraction eluted with chloroform is obtained 0.22 g of farnesyl 5-(4-hydroxy-3-methoxyphenyl)-2,4-pentadienoate (10). Spectroscopic data of the product support the structure of the formula (10) below.

Provenance & Evidence