反应详情

温度

80 °C

1.38 kg of zinc powder and 15 g of ammonium chloride in 3.25 liters of ethanol to which have been added 600 ml of water are heated to 80° C. 2.5 mole (648 g) of 3-benzyloxy-6-methoxynitrobenzene is added little by little. Stirring is continued for 15 minutes after the end of the addition. The zinc is removed by filtering the reaction medium hot. The product crystallizes from the filtrate by cooling. After centrifuging and then washing with petrol ether, the product is dried. It melts at 81° C.

1. additionafter the end of the addition
2. customThe zinc is removed
3. filtrationby filtering the reaction medium hot
4. customThe product crystallizes from the filtrate
5. temperatureby cooling
6. washwashing with petrol ether
7. customthe product is dried