HCID 43023, compound → HCID 14751608, compound

Participants

Reaction Steps

0.01 mole of 3-methyl-6-(3-morpholinopropionyl)benzoxazolinone, prepared in stage A, is dissolved in 200 cm3 of methanol in a 250-cm3 flask equipped with a magnetic stirrer. 0.02 mole of sodium borohydride is added very slowly and with stirring. Stirring is continued for 4 hours at room temperature. The reaction medium is evaporated on a water bath under vacuum. The residue is taken up with water and the mixture is extracted several times with chloroform. The extracts are filtered and evaporated to dryness on a water bath under vacuum and the product is recrystallized in cyclohexane.

Provenance & Evidence