HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-(5-Bromo-2-thienyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-(2'-Thienyl)pyridine | HCID 76832 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(5-Bromo-2-thienyl)pyridine | HCID 736483 | — |
Reaction Steps
Bromine, 16 g (0.1 mol), was added to a solution of 8.05 g (0.05 mol) of 2-(2-thienyl)pyridine in 250 ml of methylene chloride. After stirring for 10 minutes, the reaction mixture was washed with 10% aqueous sodium carbonate solution, dried and evaporated. Crystallization from ethanol gave 9.5 g of the title compound with m.p. 85°-87°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05132310 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-f88f4db035104b089b010665f79d2b3e |
| Source note | uspto-grants-1992_07 |