反应详情

A 2.0 g amount of tetrafluoroisophthalonitrile was heated under reflux in 40 ml of methanol for 4 hours. The methanol was distilled off in vacuo to approximately one-fifth volume and ice water was then poured to the resultant mixture. The precipitated crystal was collected by filtration and was then washed with water and a small amount of cold methanol. After drying in vacuo, 1.6 g of the desired compound No. 20 was obtained.

1. distillationThe methanol was distilled off in vacuo to approximately one-fifth volume and ice water
2. additionwas then poured to the resultant mixture
3. filtrationThe precipitated crystal was collected by filtration
4. washwas then washed with water
5. dry with materialAfter drying in vacuo, 1.6 g of the desired compound No
6. custom20 was obtained