N,N-Dimethylaniline → HCID 19887689, compound

HRID 654533Notes

Reaction equation

HRID 654533 reaction equation
[CH3:1][CH:2](Cl)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:10][N:11]([CH3:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[F:19][Sb-:20]([F:25])([F:24])([F:23])([F:22])[F:21].[Na+]>CO>[F:19][Sb-:20]([F:25])([F:24])([F:23])([F:22])[F:21].[CH3:1][CH:2]([N+:11]([CH3:18])([CH3:10])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 949N,N-DimethylanilineHCID 12648(1-Chloroethyl)benzeneHCID 16689647Sodium hexafluoroantimonate

Product 1

HCID 19887689HCID 19887689, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4.218 g (0.03 mol) of α-methylbenzyl chloride and 3.638 g (0.03 mol) of N,N-dimethylaniline were reacted in 40 ml of methanol at 40° C. for 3 days. After the reaction, the solvent was evaporated in vacuo and ether-water was added to the residue to extract unreacted reactants in the etherial layer. To the aqueous layer was added 7.77 g (0.03 mol) of sodium hexafluoroantimonate. The resulting crystals were suction filtered, washed and dried to give the title compound.

Workup

  1. customAfter the reaction
  2. customthe solvent was evaporated in vacuo and ether-water
  3. additionwas added to the residue
  4. extractionto extract unreacted reactants in the etherial layer
  5. filtrationfiltered
  6. washwashed
  7. customdried

Sources & evidence

ORD record
ord-d80d8268f58f4eb0bcad855845c0352c
Source dataset
uspto-grants-1992_07
Patent number
US05132377

Reaction notes

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