HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 19761562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | HCID 10753946 | HCID 10753946 | — |
| Reactant | HCID 19761541 | HCID 19761541 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | HCID 19761562 | HCID 19761562 | — |
Reaction Steps
A mixture of 3-(naphth-2-ylmethoxy)benzaldehyde, ethyl bromoacetate and zinc was reacted using the procedure described in Example 2. There was thus obtained ethyl 3-hydroxy-3-[3-(naphth-2-ylmethoxy)phenyl)propionate which was reduced with lithium aluminium hydride using the conditions described in note d above to give 3-[3-(naphth-2-ylmethoxy)phenyl]propane-1,3-diol as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05132328 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-a19624342dbf4894bbac717082d47336 |
| Source note | uspto-grants-1992_07 |